Selected Papers

  • Rosenblum, M., Qian, T., Du, Y., and Qiu, H., Fisher, A. (In Press) Multiple Testing Procedures for Adaptive Enrichment Designs: Combining Group Sequential and Reallocation Approaches. Biostatistics.
  • Rosenblum, M., Thompson, R., Luber, B., Hanley, D. (In Press) Group Sequential Designs with Prospectively Planned Rules for Subpopulation Enrichment. Statistics in Medicine.
  • Hanley, D. F., Thompson, R. E., Muschelli, J., Rosenblum, M., McBee, N., Lane, K., Bistran-Hall, A. J., Mayo, S. W., Keyl, P., Gandhi, D., Morgan, T. C., Ullman, N., Mould, W. A., Carhuapoma, J. R., Kase, C., Ziai, W., Thompson, C. B., Yenokyan, G., Huang, E., Broaddus, W. C., Graham, R. S., Aldrich, E. F., Dodd, R., Wijman, C., Caron, J-L., Huang, J., Camarata, P., Mendelow, A. D., Gregson, B., Janis, S., Vespa, P., Martin, N., Awad, I., Zuccarello, M., for the MISTIE II Investigators. (In Press) Safety and efficacy of minimally invasive surgery plus alteplase in intracerebral haemorrhage evacuation (MISTIE): a randomized, controlled, open-label, phase 2 trial. Lancet Neurology.
  • Hanley, D.F., Lane, K., McBee, N., Ziai, W, Tuhrim, S., Lees, K.R., Dawson, J., Gandhi, D., Ullman, N., Mould, W.A., Mayo, S.W., Mendelow, A.D., Gregson, B., Butcher, K., Vespa, P., Wright, D.W., Kase, C.S., Carhuapoma, J.R., Keyl, P.M., Diener-West, M., Betz, J.F., Thompson, C., Sugar, E.A., Yenokyan, G., Janis, S., John, S., Harnof, S., Lopez, G., Aldrich, E.F., Harrigan, M.R., Ansari, S., Jallo, J., Caron, J-L., LeDoux, D., Adeoye, O., Zuccarello, M., Adams, H.P., Rosenblum, M., Thompson, R.E., Awad, I.A., for the CLEAR III Investigators. (In Press) CLEAR III trial results: thrombolytic removal of intraventricular hemorrhage in treating severe stroke. The Lancet.
  • Patil, P., Colantuoni, E., Leek, J. T., Rosenblum, M. (2016) Measuring the Contribution of Genomic Predictors to Improving Estimator Precision in Randomized trials. Contemporary Clinical Trials Communications. 48-54.
  • Diaz, I., Colantuoni, E., Rosenblum, M. (2016) Enhanced Precision in the Analysis of Randomized Trials with Ordinal Outcomes. Biometrics. (72) 422-431 [LINK]
  • Rosenblum, M. (2015) Adaptive Randomized Trial Designs that Cannot Be Dominated By Any Standard Design at the Same Total Sample Size. 102(1). 191-202. Biometrika. [LINK]
  • Diaz, I. and Rosenblum, M. (2015) Targeted Maximum Likelihood Estimation Using Exponential Families. International Journal of Biostatistics. 11(2), 233-251. Working paper available here:
  • Webb, A., Ullman, N., Morgan, T., Muschelli, J., Kornbluth, J., Awad, I., Mayo, S., Rosenblum, M., Ziai, W., Zuccarrello, M., Aldrich, F., John, S., Harnof, S., Lopez, G., Broaddus, W., Wijman, C., Vespa, P., Bullock, R., Haines, S., Cruz-Flores, S., Tuhrim, S., Hill, M., Narayan, R., Hanley, D., (2015) Accuracy of the ABC/2 score for intracerebral hemorrhage: Systematic review and analysis of MISTIE, CLEAR-IVH, CLEAR III. Stroke.
  • Colantuoni, E. and Rosenblum, M. (2015) Leveraging Prognostic Baseline Variables to Gain Precision in Randomized Trials. Statistics in Medicine. doi: 10.1002/sim.6507 [LINK]
  • Rosenblum, M, Liu, H., Yen, E.-H. (2014) “Optimal Tests of Treatment Effects for the Overall Population and Two Subpopulations in Randomized Trials, Using Sparse Linear Programming” Journal of the American Statistical Association (Theory and Methods). Volume 109. Issue 507. 1216-1228. [LINK]
  • Rudolph KE, Dìaz I, Rosenblum M, Stuart EA. (2014) Estimating population treatment effects from a survey subsample. American Journal of Epidemiology 180(7): 737-48. [LINK]
  • Rosenblum, M, (2014) “Uniformly Most Powerful Tests for Simultaneously Detecting a Treatment Effect in the Overall Population and at Least One Subpopulation” Journal of Statistical Planning and Inference. Volume 155. 107-116.
  • Bolton, P., Bass, J., Zangana, G.A.S., Kamal, T., Murray, S., Kaysen, D., Lejuez, C.W., Lindgren, K., Pagoto, S., Murray, L. Skavenski, S., Amin, N., Ahmed, A., Rosenblum, M. (2014) A randomized controlled trial of mental health interventions for survivors of systemic violence in Kurdistan, Northern Iraq. BMC Psychiatry. Volume 14:1693.
  • Rosenblum M. (2013) “Confidence intervals for the selected population in randomized trials that adapt the population enrolled” Biometrical Journal. 55(3):322-340. [LINK]
  • Rosenblum M, van der Laan MJ. (2011) “Optimizing Randomized Trial Designs to Distinguish  which Subpopulations Benefit from Treatment” Biometrika, 98(4): 845-860. [LINK]
  • Rosenblum M, van der Laan MJ. (2010) “Simple, Efficient Estimators of Treatment Effects in Randomized Trials Using Generalized Linear Models to Leverage Baseline Variables” The International Journal of Biostatistics6(1): Article 13. [LINK]
  • Shiboski S, Rosenblum M, Jewell N. (2010) “The Impact of Secondary Condom Interventions on the Interpretation of Results from HIV Prevention Trials” Statistical Communications in Infectious Diseases, 2(1): Article 2. [LINK]
  • Rosenblum M, van der Laan MJ. (2010) “Targeted Maximum Likelihood Estimation of the Parameter of a Marginal Structural Model” International Journal of Biostatistics, 6(2): Article 19. [LINK]
  • Rosenblum M, Jewell NP, van der Laan, MJ, Shiboski S, van der Straten A, Padian N. (2009) “Analyzing Direct Effects in Randomized Trials with Secondary Interventions: An Application to HIV Prevention Trials” Journal of the Royal Statistical Society: Series A, (Statistics in Society), 172(2): 443-465(23). [LINK] Slides from talk at Fred Hutchinson Cancer Research Center on this work.[PDF]
  • Rosenblum M, van der Laan MJ. (2009) “Confidence Intervals for the Population Mean Tailored to Small Sample Sizes, with Applications to Survey Sampling”International Journal of Biostatistics, 5(1): Article 4. [LINK]
  • Rosenblum M, Deeks SG, van der Laan M, Bangsberg DR. (2009) “The Risk of Virologic Failure Decreases with Duration of HIV Suppression, at Greater than 50% Adherence to Antiretroviral Therapy” PLoS ONE, 4(9): e7196. [LINK]
  • Rosenblum M, van der Laan MJ. (September 2009) “Using Regression Models to Analyze Randomized Trials: Asymptotically Valid Hypothesis Tests Despite Incorrectly Specified Models” Biometrics, 65(3): 937-945. [LINK] Slides from a talk at Berkeley Statistics Colloquium on this work. [PDF]
  • Padian N, van der Straten A, Ramjee G, Chipato T, de Bruyn G, Blanchard K, Shiboski S, Montgomery ET, Fancher H, Cheng H, Rosenblum M, van der Laan MJ, Jewell N, McIntyre J, the MIRA team. (2007) “Diaphragm and lubricant gel for prevention of HIV acquisition in southern African women: a randomised controlled trial” The Lancet370(9583): 251-261. [LINK]